Mostrar el registro sencillo del ítem
Acrylic Bone Cement Incorporated with Low Chitosan Loadings
| dc.contributor.author | Valencia Zapata, Mayra Eliana | |
| dc.contributor.other | Mina Hernandez, José Herminsul | |
| dc.contributor.other | Grande Tova, Carlos David | |
| dc.date.accessioned | 2022-11-15T21:03:49Z | |
| dc.date.available | 2022-11-15T21:03:49Z | |
| dc.date.issued | 2020-07-21 | |
| dc.date.submitted | 2020-07-05 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12834/934 | |
| dc.description.abstract | Despite the potential of acrylic bone cement (ABC) loaded with chitosan (CS) for orthopedic applications, there are only a few in vitro studies of this composite with CS loading ≤ 15 wt.% evaluated in bioactivity tests in simulated body fluid (SBF) for duration > 30 days. The purpose of the present work was to address this shortcoming of the literature. In addition to bioactivity, a wide range of cement properties were determined for composites with CS loading ranging from 0 to 20 wt.%. These properties included maximum exotherm temperature (Tmax), setting time (tset), water contact angle, residual monomer content, flexural strength, bending modulus, glass transition temperature, and water uptake. For cement with CS loading ≥ 15 wt.%, there was an increase in bioactivity, increase in biocompatibility, decrease in Tmax, increase in tset, all of which are desirable trends, but increase in residual monomer content and decrease in each of the mechanical properties, with each of these trends, were undesirable. Thus, a composite with CS loading of 15 wt.% should be further characterized to explore its suitability for use in low-weight-bearing applications, such as bone void filler and balloon kyphoplasty | spa |
| dc.format.mimetype | application/pdf | spa |
| dc.language.iso | eng | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
| dc.source | Polymers | spa |
| dc.title | Acrylic Bone Cement Incorporated with Low Chitosan Loadings | spa |
| dcterms.bibliographicCitation | 1. Magnan, B.; Bondi, M.; Maluta, T.; Samaila, E.; Schirru, L.; Dall’Oca, C. Acrylic bone cement: Current concept review. Musculoskelet. Surg. 2013, 97, 93–100 | spa |
| dcterms.bibliographicCitation | 2. Khandaker, M.; Vaughan, M.B.; Morris, T.L.; White, J.J.; Meng, Z. Effect of additive particles on mechanical, thermal, and cell functioning properties of poly (methyl methacrylate) cement. Int. J. Nanomed. 2014, 2699–2712 | spa |
| dcterms.bibliographicCitation | 3. Soleymani Eil Bakhtiari, S.; Karbasi, S.; Hassanzadeh Tabrizi, S.A.; Ebrahimi-Kahrizsangi, R.; Salehi, H. Evaluation of the effects of chitosan/multiwalled carbon nanotubes composite on physical, mechanical and biological properties of polymethyl methacrylate-based bone cements. Mater. Technol. 2019, 35, 267–280 | spa |
| dcterms.bibliographicCitation | 4. Lewis, G. Alternative acrylic bone cement formulations for cemented arthroplasties: Present status. key issues, and future prospects. J. Biomed. Mater. Res. B Appl. Biomater. 2008, 84, 301–319 | spa |
| dcterms.bibliographicCitation | 5. Wang, M.; Sa, Y.; Li, P.; Guo, Y.; Du, Y.; Deng, H.; Jiang, T.; Wang, Y. A versatile and injectable poly(methyl methacrylate) cement functionalized with quaternized chitosan-glycerophosphate/nanosized hydroxyapatite hydrogels. Mater. Sci. Eng. C 2018, 90, 264–272 | spa |
| dcterms.bibliographicCitation | 6. De Mori, A.; Di Gregorio, E.; Kao, A.P.; Tozzi, G.; Barbu, E.; Sanghani-Kerai, A.; Draheim, R.R.; Roldo, M. Antibacterial PMMA Composite Cements with Tunable Thermal and Mechanical Properties. ACS Omega 2019, 4, 19664–19675. | spa |
| dcterms.bibliographicCitation | 7. Islam, M.M.; Shahruzzaman, M.; Biswas, S.; Nurus Sakib, M.; Rashid, T.U. Chitosan based bioactive materials in tissue engineering applications—A review. Bioact. Mater. 2020, 5, 164–183 | spa |
| dcterms.bibliographicCitation | 8. Barradas, A.M.C.; Yuan, H.; Van Blitterswijk, C.A.; Habibovic, P. Osteoinductive biomaterials: Current knowledge of properties, experimental models and biological mechanisms. Eur. Cells Mater. 2011, 21, 407–429 | spa |
| dcterms.bibliographicCitation | 9. Bakshi, P.S.; Selvakumar, D.; Kadirvelu, K.; Kumar, N.S. Chitosan as an environment friendly biomaterial— A review on recent modifications and applications. Int. J. Biol. Macromol. 2020, 150, 1072–1083 | spa |
| dcterms.bibliographicCitation | 10. Dunne, N.; Buchanan, F.; Hill, J.; Newe, C.; Tunney, M.; Brady, A.; Walker, G. In vitro testing of chitosan in gentamicin-loaded bone cement: No antimicrobial effect and reduced mechanical performance. Acta Orthop. 2008, 79, 851–860 | spa |
| dcterms.bibliographicCitation | 11. Lin, M.C.; Chen, C.C.; Wu, I.T.; Ding, S.J. Enhanced antibacterial activity of calcium silicate-based hybrid cements for bone repair. Mater. Sci. Eng. C 2020, 110, 110727 | spa |
| dcterms.bibliographicCitation | 12. Shi, Z.; Neoh, K.G.; Kang, E.T.; Wang, W. Antibacterial and mechanical properties of bone cement impregnated with chitosan nanoparticles. Biomaterials 2006, 27, 2440–2449 | spa |
| dcterms.bibliographicCitation | 13. Tavakoli, M.; Bakhtiari, S.S.E.; Karbasi, S. Incorporation of chitosan/graphene oxide nanocomposite in to the PMMA bone cement: Physical, mechanical and biological evaluation. Int. J. Biol. Macromol. 2020, 149, 783–793 | spa |
| dcterms.bibliographicCitation | 14. Liu, B.; Li, M.; Yin, B.; Zou, J.; Zhang, W.; Wang, S.-Y. Effects of Incorporating Carboxymethyl Chitosan into PMMA Bone Cement Containing Methotrexate. PLoS ONE 2015, 10, 144407 | spa |
| dcterms.bibliographicCitation | 15. Endogan, T.; Kiziltay, A.; Kose, G.T.; Comunoglu, N.; Beyzadeoglu, T.; Hasirci, N. Acrylic Bone Cements: Effects of the Poly (methyl methacrylate) Powder Size and Chitosan Addition on Their Properties. J. Appl. Polym. Sci. Polym. Sci. 2014, 131, 39662 | spa |
| dcterms.bibliographicCitation | 16. Deb, S.; Koller, G. Chapter 8. Acrylic bone cement: Genesis and evolution. In Orthopaedic Bone Cements; Deb, S., Ed.; Woodhead Publishing Limited: Cambridge, UK, 2008; pp. 167–182, ISBN 978-1-84569-517-0. | spa |
| dcterms.bibliographicCitation | 17. Miyazaki, T.; Ohtsuki, C. Design of bioactive bone cement based on organic–inorganic hybrids. In Orthopaedic Bone Cements; Deb, S., Ed.; Woodhead Publishing Limited: Cambridge, UK, 2008; p. 400. | spa |
| dcterms.bibliographicCitation | 18. International Standard ISO 5833. Implants for Surgery-Acrylic Resin Cements. ISO: Geneva, Switzerland, 2002; pp. 1–22. | spa |
| dcterms.bibliographicCitation | 19. Kokubo, T.; Takadama, H. How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 2006, 27, 2907–2915. | spa |
| dcterms.bibliographicCitation | 20. ASTM F1635-16. Standard Test Method for In Vitro Degradation Testing of Hydrolytically Degradable Polymer Resins and Fabricated Forms for Surgical Implants. American Society of Testing Materials: West Conshohocken, PA, USA, 2016; pp. 1–5. | spa |
| dcterms.bibliographicCitation | 21. Pahlevanzadeh, F.; Bakhsheshi-Rad, H.R.; Ismail, A.F.; Aziz, M.; Chen, X.B. Development of PMMA-Mon-CNT bone cement with superior mechanical properties and favorable biological properties for use in bone-defect treatment. Mater. Lett. 2019, 240, 9–12 | spa |
| dcterms.bibliographicCitation | 22. Vazquez-Lasa, B. Poly(methylmethacrylate) bone cement: Chemical composition and chemistry. In Orthopaedic Bone Cements; Deb, S., Ed.; Woodhead Publishing Limited: Cambridge, UK, 2008; p. 400 | spa |
| dcterms.bibliographicCitation | 23. Tan, H.; Guo, S.; Yang, S.; Xu, X.; Tang, T. Physical characterization and osteogenic activity of the quaternized chitosan-loaded PMMA bone cement. Acta Biomater. 2012, 8, 2166–2174. | spa |
| dcterms.bibliographicCitation | 24. Nazhat, S.N.; Cauich Rodriguez, J.V. Dynamic mechanical properties of bone cements. In Orthopaedic Bone Cements; Deb, S., Ed.; Woodhead Publishing: Cambridge, UK, 2008; pp. 296–310. | spa |
| dcterms.bibliographicCitation | 25. Varlamov, V.P.; Il’ina, A.V.; Shagdarova, B.T.; Lunkov, A.P.; Mysyakina, I.S. Chitin/Chitosan and Its Derivatives: Fundamental Problems and Practical Approaches. Biochemistry 2020, 85, 154–176. | spa |
| dcterms.bibliographicCitation | 26. Tiainen, H.; Wohlfahrt, J.C.; Verket, A.; Lyngstadaas, S.P.; Haugen, H.J. Bone formation in TiO 2 bone scaffolds in extraction sockets of minipigs. Acta Biomater. 2012, 8, 2384–2391. | spa |
| dcterms.bibliographicCitation | 27. He, Q.; Chen, H.; Huang, L.; Dong, J.; Guo, D.; Mao, M.; Kong, L.; Li, Y.; Wu, Z.; Lei, W. Porous Surface Modified Bioactive Bone Cement for Enhanced Bone Bonding. PLoS ONE 2012, 7, e42525 | spa |
| dcterms.bibliographicCitation | 28. May-Pat, A.; Herrera-Kao, W.; Cauich-Rodríguez, J.V.; Cervantes-Uc, J.M.; Flores-Gallardo, S.G. Comparative study on the mechanical and fracture properties of acrylic bone cements prepared with monomers containing amine groups. J. Mech. Behav. Biomed. Mater. 2012, 6, 95–105 | spa |
| dcterms.bibliographicCitation | 29. Valencia Zapata, M.E.; Mina Hernandez, J.H.; Grande Tovar, C.D.; Valencia Llano, C.H.; Diaz Escobar, J.A.; Vázquez-Lasa, B.; San Román, J.; Rojo, L.; Rojo, L. Novel Bioactive and Antibacterial Acrylic Bone Cement Nanocomposites Modified with Graphene Oxide and Chitosan. Int. J. Mol. Sci. 2019, 20, 2938 | spa |
| dcterms.bibliographicCitation | 30. Kühn, K.-D. Bone Cements; Springer: Berlin, Germany, 2000; ISBN 9783642641152. | spa |
| dcterms.bibliographicCitation | 31. Lewis, G. Properties of nanofiller-loaded poly (methyl methacrylate) bone cement composites for orthopedic applications: A review. J. Biomed. Mater. Res.—Part B Appl. Biomater. 2017, 105, 1260–1284 | spa |
| dcterms.bibliographicCitation | 32. Depan, D.; Shah, J.S.; Misra, R.D.K. Degradation mechanism and increased stability of chitosan-based hybrid scaffolds cross-linked with nanostructured carbon: Process-structure-functional property relationship. Polym. Degrad. Stab. 2013, 98, 2331–2339 | spa |
| dcterms.bibliographicCitation | 33. Ruiz, S.; Tamayo, J.A.; Ospina, J.D.; Navia Porras, D.P.; Valencia Zapata, M.E.; Mina Hernandez, J.H.; Valencia, C.H.; Zuluaga, F.; Grande Tovar, C.D. Antimicrobial Films Based on Nanocomposites of Chitosan / Poly ( vinyl alcohol )/ Graphene Oxide for Biomedical Applications. Biomolecules 2019, 9, 109 | spa |
| dcterms.bibliographicCitation | 34. Safadi, F.F.; Barbe, M.F.; Abdelmagid, S.M.; Rico, M.C.; Aswad, R.A.; Litvin, J.; Popoff, S.N. Bone Structure, Development and Bone Biology. In Bone Pathology; Khurana, J.S., Ed.; Humana Press: New York, NY, USA, 2009; Volume 2, pp. 1–50, ISBN 9781588297662. | spa |
| dcterms.bibliographicCitation | 35. Mirmusavi, M.H.; Zadehnajar, P.; Semnani, D.; Karbasi, S.; Fekrat, F.; Heidari, F. Evaluation of physical, mechanical and biological properties of poly 3-hydroxybutyrate-chitosan-multiwalled carbon nanotube/silk nano-micro composite scaffold for cartilage tissue engineering applications. Int. J. Biol. Macromol. 2019, 132, 822–835 | spa |
| dcterms.bibliographicCitation | 36. Islas-Blancas, M.E.; Cervantes-Uc, J.M. Characterization of bone cements prepared with functionalized methacrylates and hydroxyapatite. J. Biomater. Sci. Polym. Ed. 2001, 12, 893–910 | spa |
| datacite.rights | http://purl.org/coar/access_right/c_abf2 | spa |
| oaire.resourcetype | http://purl.org/coar/resource_type/c_6501 | spa |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
| dc.audience | Público general | spa |
| dc.identifier.doi | 10.3390/polym12071617 w | |
| dc.identifier.instname | Universidad del Atlántico | spa |
| dc.identifier.reponame | Repositorio Universidad del Atlántico | spa |
| dc.rights.cc | Attribution-NonCommercial 4.0 International | * |
| dc.subject.keywords | acrylic bone cement; bioactivity; biocompatibility; chitosan; poly (methyl methacrylate) | spa |
| dc.type.driver | info:eu-repo/semantics/article | spa |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | spa |
| dc.type.spa | Artículo | spa |
| dc.publisher.place | Barranquilla | spa |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | spa |
| dc.publisher.sede | Sede Norte | spa |
Ficheros en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
Excepto si se señala otra cosa, la licencia del ítem se describe como http://creativecommons.org/licenses/by-nc/4.0/
Tecnología DSpace implementada por 